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Cell viability of proximal renal tubule cell lines A) RPTEC and B) HK-2 suspended in various concentrations (0 μM, 6 μM, 36 μM, 72 μM, 144 μM and 200 μM) of chemical agents. TOB = tobramycin, PMB = polymyxin B.

Journal: RSC Medicinal Chemistry

Article Title: Amphiphilic nebramine analogs synergize with β-lactam/β-lactamase inhibitor combinations, including cefepime–taniborbactam and meropenem–xeruborbactam against metallo-β-lactamase-carrying Pseudomonas aeruginosa †

doi: 10.1039/d5md00375j

Figure Lengend Snippet: Cell viability of proximal renal tubule cell lines A) RPTEC and B) HK-2 suspended in various concentrations (0 μM, 6 μM, 36 μM, 72 μM, 144 μM and 200 μM) of chemical agents. TOB = tobramycin, PMB = polymyxin B.

Article Snippet: The RPTEC cells were cultured in T75 flasks with Dubelcco's Modified Eagle's Medium:F12 supplemented with the human telomerase reverse transcriptase immortalized RPTEC growth kit from ATCC, G418 (0.1 mg mL −1 final concentration), and 2% fetal bovine serum (FBS).

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